The medicinal plastic bottles sold on the market now are diverse, with various shapes and varieties. Faced with such a colorful plastic bottle market, how can pharmaceutical manufacturers grasp the key points when choosing and select high-quality plastic bottles.
1. Material selection is key: the main raw materials and auxiliary formula used for plastic bottles have a crucial impact on their quality and bottom. When selecting the main raw materials, there are many varieties, which requires us to investigate their comprehensive performance. Generally, high-density polyethylene and polypropylene bottles are used for tablets. If transparency is required, PET bottles can be used. If drugs require higher barrier performance, light blocking and opacity, brown PET bottles are selected, and PEN bottles have better barrier performance. Generally, polypropylene or polyester bottles are used as the main raw materials for medicinal liquid bottles.
2. Sealing and permeability: Sealing and water vapor permeability are two important technical indicators of medicinal plastic bottles, which have a crucial impact on the stability of the charge.
3. Stability and compatibility: When selecting plastic bottles, especially for new drugs using new plastic bottles (or new materials, new processes), loading tests should be conducted first to examine the stability of the loading and the compatibility between the plastic bottle and the drug. The permeation, dissolution, adsorption, chemical reaction, and denaturation between drugs and plastic bottle materials must be determined through scientific testing.
4. Product quality and assurance system: Pharmaceutical plastic bottle manufacturers should have corresponding national and industry standards. At the same time, a comprehensive and accurate evaluation of the software and hardware facilities, technical equipment, and overall quality level of the manufacturer should be made.
